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KMID : 0364820220580040338
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Korean Journal of Microbiology
2022 Volume.58 No. 4 p.338 ~ p.341
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Complete genome sequence of Treponema denticola KCOM 3500 isolated from the subgingival plaque of a human chronic periodontitis lesion
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Park Soon-Nang
Lim Yun-Kyong
Kook Joong-Ki
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Abstract
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Treponema denticola is a strictly anaerobic, Gram-negative, non-spore forming and motile, spiral-shaped cells. It is a major causative agent of periodontitis and is related to systemic diseases such as Alzheimer’s disease and cardiovascular diseases. T. denticola KCOM 3500 (= ChDC P019-Td1) was isolated from human chronic periodontitis lesion. In this study, we present the whole genome sequence of T. denticola KCOM 3500. The genome of strain KCOM 3500 was 2,778,422 bp in length and contained 2,507 protein-coding sequences, 6 rRNAs, and 44 tRNAs. The G + C content of it was 38.1%. It contained a dentilisin complex serine proteinase, a strong protease.
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KEYWORD
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Treponema denticola, chronic periodontitis, human
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